Endocrine Abstracts

History: 57yrs old gentleman presented with c/o-Shortness of breath confusion weakness Tired Having poor appetite Poor mobility generally unwell.P/M/H: Diagnosed with Medullary Thyroid Carcinoma as a part of MEN2A at the age of 32 yrs had a thyroidectomy and lymph node clearance in 1997 followed by a few months later by sternotomy and mediastinal node resection. Bony metastasis. Residual Horner’s syndrome. Developed Renal, liver and Bone metastasis ...

Background: Congenital leptin deficiency (CLD) is characterized by severe early-onset obesity due to hyperphagia and impaired satiety. The impact of obesity in obstructive sleep apnoea hypopnoea syndrome (OSAHS) was originally reported as mechanical, but recent data suggest that adipokines may influence central ventilation. We highlight that treatment with recombinant human leptin (RHL) in CLD with OSAHS improves ventilation before weight loss.Case prese...